Non-surgical options for neuropathy may include custom topical creams and lotions. The most commonly used topical medications in the treatment of neuropathy are: gabapentin (Neurontin), ketamine, cyclobenzaprine (Flexeril), amitriptyline (Eleavil) fluribiprofen (Ansaid) and ketoprofen (Orudis) along with local anesthetic such as lidocaine or prilocaine.